INCFinder

GenBank ID	LC501629.1
Plasmid name	p20C122-1 (contig 2)
Classification	C1
Length	57 623 bp
GC content	52%
Organism	Escherichia coli 20-Ec-C-122
Curation	Manually annotated

Plasmid map

Notes

Incomplete plasmid sequence (p20C122-1 contig2). The entire plasmid sequence may be assembled from the 4 contigs GenBank LC501628.1 - LC501631.1. RHS1, orf1832 and the empty site of I2 insertion are intact, the site of I1 insertion is missing.

Characteristic genes

Gene name	Length	Location	Length of alignment	Identity (%)	Coverage (%)	E-value
repA	1101	17147 - 18247 (-)	1101	100	100	0
RHS1	4254	40244 - 44497 (-)	4254	100	100	0

Antimicrobial resistance genes

Type match	Model name	Model type	Location	E-value	Identity
Perfect	cmlA5	protein homolog model	55810 - 57069(+)	0	100 %
major facilitator superfamily (MFS) antibiotic efflux pump AMR Gene Family Directed pumping of antibiotic out of a cell to confer resistance. Major facilitator superfamily (MFS) transporters and ABC transporters comprise the two largest and most functionally diverse of the transporter superfamilies. However, MFS transporters are distinct from ABC transporters in both their primary sequence and structure and in the mechanism of energy coupling. As secondary transporters they are, like RND and SMR transporters, energized by the electrochemical proton gradient. chloramphenicol Antibiotic Chloramphenicol is a bacteriostatic antimicrobial originally derived from the bacterium Streptomyces venezuelae. It was the first antibiotic to be manufactured synthetically on a large scale. It functions by inhibiting peptidyl transferase activity of the bacterial ribosome, binding to A2451 and A2452 residues in the 23S rRNA of the 50S ribosomal subunit and preventing peptide bond formation. phenicol antibiotic Drug Class Phenicols are broad spectrum bacteriostatic antibiotics acting on bacterial protein synthesis. More specifically, the phenicols block peptide elongation by binding to the peptidyltansferase centre of the 70S ribosome. efflux pump complex or subunit conferring antibiotic resistance Efflux Component Efflux proteins that pump antibiotic out of a cell to confer resistance. antibiotic efflux Resistance Mechanism Antibiotic resistance via the transport of antibiotics out of the cell.