INCFinder

GenBank ID	CP080515.1
Plasmid name	pSA18578_2
Classification	-
Length	129 660 bp
GC content	51%
Organism	Salmonella enterica subsp. enterica serovar Minnesota strain SA18578
Curation	Manually annotated

Plasmid map

Notes

The majority of the IncC backbone including the RHS and orf1832/1847 genes and the site of I2 insertion is missing. The empty site of I1 insertion is intact. The plasmid cannot be classified into Type1/2.

Characteristic genes

Gene name	Length	Location	Length of alignment	Identity (%)	Coverage (%)	E-value
repA	684	128977 - 129660 (+)	684	100	62	0
AriB	62	28301 - 28362 (+)	62	98	2	8.9422E-25

Antimicrobial resistance genes

Type match	Model name	Model type	Location	E-value	Identity
Strict	APH(3')-Ia	protein homolog model	43865 - 44680(-)	0	98.52 %
APH(3') AMR Gene Family Phosphorylation of 2-deoxystreptamine aminoglycosides on the hydroxyl group at position 3' neomycin Antibiotic Neomycin is an aminoglycoside antibiotic used to treat different types of bacterial infections. Neomycin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth. ribostamycin Antibiotic Ribostamycin is an aminoglycoside antibiotic used to treat different types of bacterial infections. Ribostamycin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth. kanamycin A Antibiotic Kanamycin is an aminoglycoside antibiotic used to treat different types of bacterial infections. Kanamycin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth. G418 Antibiotic A gentamicin class aminoglycoside antibiotic often used in mammalian cell culture work as a selectable marker for the neo cassette (APH3'). paromomycin Antibiotic An aminoglycoside antibiotic used for the treatment of parasitic infections. It is similar to neomycin sharing a similar spectrum of activity, but its hydroxyl group at the 6'-position instead of an amino group makes it resistant to AAC(6') modifying enzymes. lividomycin A Antibiotic Lividomycin A is a pentasaccharide antibiotic which interferes with bacterial protein synthesis. lividomycin B Antibiotic Lividomycin B is a derivative of lividomycin A with a removed mannose group (demannosyllividomycin A). Livodomycins interfere with bacterial protein synthesis. aminoglycoside antibiotic Drug Class Aminoglycosides are a group of antibiotics that are mostly effective against Gram-negative bacteria. These molecules consist of aminated sugars attached to a dibasic cyclitol. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit (some work by binding to the 50S subunit), inhibiting the translocation of the peptidyl-tRNA from the A-site to the P-site and also causing misreading of mRNA, leaving the bacterium unable to synthesize proteins vital to its growth. antibiotic inactivation Resistance Mechanism Enzymatic inactivation of antibiotic to confer drug resistance.